A hierarchical 3D camellia-like molybdenum tungsten disulfide architectures for the determination of morphine and tramadol

Somayeh Mohammadi; Mohammad Ali Taher; Hadi Beitollahi

doi:10.1007/s00604-020-4134-x

A hierarchical 3D camellia-like molybdenum tungsten disulfide architectures for the determination of morphine and tramadol

Mikrochim Acta. 2020 May 4;187(5):312. doi: 10.1007/s00604-020-4134-x.

Authors

Somayeh Mohammadi^{1

2}, Mohammad Ali Taher³, Hadi Beitollahi⁴

Affiliations

¹ Department of Chemistry, Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman, 7616914111, Iran. [email protected].
² Young Researchers Society, Shahid Bahonar University of Kerman, Kerman, Iran. [email protected].
³ Department of Chemistry, Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman, 7616914111, Iran. [email protected].
⁴ Environment Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, 7631818356, Iran.

PMID: 32367346
DOI: 10.1007/s00604-020-4134-x

Abstract

A practical technique was applied to fabricate MoWS₂ nanocomposite through a one-pot hydrothermal method for use as the electrocatalyst. The characterization of MoWS₂ nanocomposite was investigated by several techniques to identify the size, crystal structure, and elemental composition. MoWS₂ nanocomposite exhibited a unique and well-defined hierarchical structure with neatly and densely piled nanopetals acting as the active sites in the electrocatalytic reactions. A carbon screen-printed electrode (CSPE) modified with interesting MoWS₂ nanopetals (MoWS₂/CSPE) was constructed. Subsequently, the electrochemical oxidation of morphine on fabricated MoWS₂/CSPE was studied. Experimental results confirm that under optimized conditions, the maximum oxidation current of morphine occurs at 275 mV in the case of MoWS₂/CSPE that is around 100 mV more negative than that observed in the case of the unmodified CSPE and about 2.6 times increase was observed for the oxidation peak current. The analytical approach was obtained by differential pulse voltammetry in accordance with the relationship between the oxidation peak current and the morphine concentration. The oxidation peak currents for morphine were found to vary linearly with its concentrations in the range of 4.8 × 10^-8-5.05 × 10^-4 M with the detection limit of 1.44 × 10^-8 M. Two completely separated signals occured at the potentials of 275 mV and 920 mV for oxidation of morphine and tramadol at the surface of MoWS₂/CSPE which are sufficient for determination of morphine in the presence of tramadol. The presence of morphine was also detected in real samples using the introduced approach. Graphical abstract Schematic representation of fabrication of the MoWS₂ nanocomposite through a one-pot hydrothermal method for use as the electrocatalyst. A carbon screen-printed electrode was modified with MoWS₂ nanocomposite. Subsequently, the electrochemical oxidation of morphine on the fabricated electrode was studied.

Keywords: 3D hierarchical MoWS2; Electrochemical detection; Morphine; Screen printed electrode; Tramadol.

MeSH terms

Carbon / chemistry
Electrochemical Techniques / methods*
Electrodes
Humans
Limit of Detection
Molybdenum / chemistry
Morphine / urine*
Nanocomposites / chemistry*
Reproducibility of Results
Sulfides / chemistry
Tramadol / urine*
Tungsten Compounds / chemistry

Substances

Sulfides
Tungsten Compounds
Tramadol
Carbon
Morphine
Molybdenum