Asymptomatic Seroconversion of Immunoglobulins to SARS-CoV-2 in a Pediatric Dialysis Unit

David S Hains; Andrew L Schwaderer; Aaron E Carroll; Michelle C Starr; Amy C Wilson; Fatima Amanat; Florian Krammer

doi:10.1001/jama.2020.8438

Asymptomatic Seroconversion of Immunoglobulins to SARS-CoV-2 in a Pediatric Dialysis Unit

JAMA. 2020 Jun 16;323(23):2424-2425. doi: 10.1001/jama.2020.8438.

Authors

David S Hains¹, Andrew L Schwaderer¹, Aaron E Carroll¹, Michelle C Starr¹, Amy C Wilson¹, Fatima Amanat², Florian Krammer²

Affiliations

¹ Department of Pediatrics, Indiana University, Indianapolis.
² Department of Microbiology, Icahn School of Medicine at Mount Sinai Medical Center, New York, New York.

Abstract

This case series describes subclinical development of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in some patients and health care workers in a pediatric dialysis unit after contact with a seropositive patient.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Antibodies, Viral / blood*
Asymptomatic Diseases*
Betacoronavirus / immunology*
COVID-19
Child
Child, Preschool
Coronavirus Infections / diagnosis
Coronavirus Infections / immunology*
Disease Transmission, Infectious
Enzyme-Linked Immunosorbent Assay
Female
Health Personnel
Hemodialysis Units, Hospital*
Humans
Immunoglobulin G / blood
Immunoglobulin M / blood
Male
Pandemics
Pneumonia, Viral / diagnosis
Pneumonia, Viral / immunology*
Prevalence
Renal Dialysis
Reverse Transcriptase Polymerase Chain Reaction
SARS-CoV-2
Seroconversion*

Substances

Antibodies, Viral
Immunoglobulin G
Immunoglobulin M