Risks of Adverse Childhood Outcomes According to Prenatal Time of Exposure to Zika Virus: Assessment in a Cohort Exposed to Zika During an Outbreak in Colombia

J Pediatric Infect Dis Soc. 2021 Apr 3;10(3):337-340. doi: 10.1093/jpids/piaa042.

Abstract

Late gestational exposure to Zika increases the odds of delay in the Bayley-II mental developmental index (MDI) in children with normal baseline neurologic assessments; 9-fold when comparing third and first trimester exposure. Risk of MDI developmental delay increases by 8% for each week of gestational age at time of exposure.

Keywords: Bayley scale; Zika; neurologic outcome; prenatal exposure.

MeSH terms

  • Child
  • Colombia / epidemiology
  • Disease Outbreaks
  • Female
  • Humans
  • Infant
  • Pregnancy
  • Pregnancy Complications, Infectious* / epidemiology
  • Zika Virus Infection* / epidemiology
  • Zika Virus*