Primary High-Grade Angiosarcoma of the Breast in a Young Woman With Breast Implants: A Rare Case and a Review of Literature

Int J Surg Pathol. 2020 Dec;28(8):906-912. doi: 10.1177/1066896920924087. Epub 2020 May 18.

Abstract

Primary angiosarcoma (AS) of the breast is an extremely unusual variant of breast malignancies, and its incidence is about 0.05% of all primary breast tumors. In this article, we present a rare case of a primary AS that developed in a young woman with breast implants. This case report emphasizes importance of early investigation for accurate diagnosis and proper management of the breast AS, along with a correlation of histopathologic, radiologic, and clinical findings.

Keywords: angiosarcoma; breast cancer; mammary implants.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Biopsy, Fine-Needle
  • Breast / diagnostic imaging
  • Breast / pathology*
  • Breast / surgery
  • Breast Implantation / adverse effects*
  • Breast Implantation / instrumentation
  • Breast Implants / adverse effects*
  • Breast Neoplasms / diagnosis
  • Breast Neoplasms / etiology*
  • Breast Neoplasms / pathology
  • Breast Neoplasms / therapy
  • Chemotherapy, Adjuvant
  • Female
  • Hemangiosarcoma / diagnosis
  • Hemangiosarcoma / etiology*
  • Hemangiosarcoma / pathology
  • Hemangiosarcoma / therapy
  • Humans
  • Lymph Node Excision
  • Magnetic Resonance Imaging
  • Mastectomy
  • Neoplasm Grading
  • Ultrasonography, Interventional
  • Ultrasonography, Mammary

Supplementary concepts

  • Angiosarcoma of the breast