Objective: To assess the predictive abilities of serum and urinary cystatin C levels for glomerular lesions in pregnant women with pre-eclampsia.
Methods: In this study, kidney function markers were compared between38 pregnant women with pre-eclampsia and 22 healthy pregnant women.
Results: The serum and urine levels of cystatin C and urea were significantly higher in the pre-eclampsia group than in the control group. Receiver operating characteristic curve analysis demonstrated that the serum cystatin C level (91.7%) had a superior diagnostic accuracy for pre-eclampsia than the other markers.
Conclusion: Serum cystatin C level maybe a significant marker of pre-eclampsia.
Keywords: Serum cystatin C; pre-eclampsia; pregnancy; urine cystatin C.