COVID-19 patients exhibit less pronounced immune suppression compared with bacterial septic shock patients

Crit Care. 2020 May 26;24(1):263. doi: 10.1186/s13054-020-02896-5.

Matthijs Kox^{1

2}, Tim Frenzel^{3

4}, Jeroen Schouten^{3

4}, Frank L van de Veerdonk^{4

5}, Hans J P M Koenen^{4

6}, Peter Pickkers^{3

4}; , on behalf of the RCI-COVID-19 study group

, on behalf of the RCI-COVID-19 study group:
Pleun Hemelaar, Remi Beunders, Johannes van der Hoeven, Sjef van der Velde, Hetty van der Eng, Noortje Rovers, Margreet Klop-Riehl, Jelle Gerretsen, Emma Kooistra, Nicole Waalders, Wout Claassen, Hidde Heesakkers, Tirsa van Schaik, Mihai Netea, Leo Joosten, Nico Janssen, Inge Grondman, Aline de Nooijer, Quirijn de Mast, Martin Jaeger, Ilse Kouijzer, Helga Dijkstra, Heidi Lemmers, Reinout van Crevel, Josephine van de Maat, Gerine Nijman, Simone Moorlag, Esther Taks, Priya Debisarun, Heiman Wertheim, Joost Hopman, Janette Rahamat-Langendoen, Chantal Bleeker-Rovers, Esther Fasse, Esther van Rijssen, Manon Kolkman, Bram van Cranenbroek, Ruben Smeets, Irma Joosten

¹ Department of Intensive Care Medicine, Radboud University Medical Center, Internal Mail 710, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. [email protected].
² Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands. [email protected].
³ Department of Intensive Care Medicine, Radboud University Medical Center, Internal Mail 710, PO Box 9101, 6500 HB, Nijmegen, The Netherlands.
⁴ Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.
⁵ Department of Internal Medicine, Radboud university medical center, Nijmegen, The Netherlands.
⁶ Department of Medical Immunology, Radboud university medical center, Nijmegen, The Netherlands.

No abstract available

Keywords: COVID; COVID-19; HLA-DR; Immune suppression; Monocytes; SARS-CoV-2; mHLA-DR.

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