Virilization of a female infant genitalia caused by a maternal androgen-producing adrenocortical tumor: A case report

Sayaka Hoshino; Kenji Obara; Tatsuhiko Hoshii; Hiroo Kuroki; Kazuhiro Watanabe; Yoshihiko Tomita

doi:10.1016/j.eucr.2020.101253

Virilization of a female infant genitalia caused by a maternal androgen-producing adrenocortical tumor: A case report

Urol Case Rep. 2020 May 15:32:101253. doi: 10.1016/j.eucr.2020.101253. eCollection 2020 Sep.

Authors

Sayaka Hoshino¹, Kenji Obara¹, Tatsuhiko Hoshii¹, Hiroo Kuroki¹, Kazuhiro Watanabe¹, Yoshihiko Tomita¹

Affiliation

¹ Division of Urology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

Abstract

A 4-month-old girl presented us with genital ambiguity. The patient had a persistent urogenital sinus, posterior labial fusion with clitoromegaly. MRI reveals ovary-like mass in left inguinal region and right abdominal cavity. Uterus and vagina was also identified. Her mother was diagnosed with a right androgen-producing adrenocortical tumor 14 months after the birth of a virilized infant.

Keywords: Maternal androgen-producing adrenocortical tumor; Urogenital sinus; Virilization of genitalia.

Publication types

Case Reports