Sweet and low-autoantibodies deny oligodendrocytes their sugar fix

Sci Immunol. 2020 Jun 5;5(48):eabd0546. doi: 10.1126/sciimmunol.abd0546.

Authors

Amanda L Hernandez¹, Kevin C O'Connor¹

Affiliation

¹ Departments of Neurology and Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA. [email protected] [email protected].

PMID: 32503879
DOI: 10.1126/sciimmunol.abd0546

Abstract

Pathogenic autoantibodies causing encephalopathy modify the expression of the glucose transporter in oligodendrocytes.

Copyright © , American Association for the Advancement of Science.

MeSH terms

Autoantibodies / immunology*
Glucose Transport Proteins, Facilitative / genetics
Glucose Transport Proteins, Facilitative / immunology
Humans
Oligodendroglia / immunology*
Oligodendroglia / pathology
Sugars / immunology*

Substances

Autoantibodies
Glucose Transport Proteins, Facilitative
Sugars