Master manipulators: how herpesviruses alter immune responses to RSV

Mucosal Immunol. 2020 Sep;13(5):715-716. doi: 10.1038/s41385-020-0313-7. Epub 2020 Jun 11.

Abstract

In this commentary on “A gammaherpesvirus licenses CD8 T cells to protect the host from pneumovirus-induced immunopathologies”, the authors highlight the growing literature suggesting that herpesvirus infections shape subsequent immune responses to other pathogens, especially by broadening CD8+T-cell responses. These observations have implications for vaccine development against other important pathogens, such as Respiratory Syncytial Virus.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • CD8-Positive T-Lymphocytes
  • Herpesviridae*
  • Humans
  • Pneumovirus*
  • Respiratory Syncytial Virus Infections*