Abstract
Syntheses and cross-reactivities with progesterone toward the same specific antibody are reported for a series of amides of 11 alpha-hydroxyprogesterone 11-hemisuccinate. Some hypotheses are made regarding the effects of the chemical structure of the substituents on the immunological properties of derivatives.
MeSH terms
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Amides / chemical synthesis
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Amides / immunology*
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Antibody Affinity*
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Antibody Specificity
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Chemical Phenomena
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Chemistry
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Chromatography / methods
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Cross Reactions
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Hydroxyprogesterones / chemical synthesis
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Hydroxyprogesterones / immunology*
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Progesterone / analogs & derivatives*
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Progesterone / immunology
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Radioimmunoassay
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Structure-Activity Relationship
Substances
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Amides
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Hydroxyprogesterones
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Progesterone
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progesterone 11-hemisuccinate