Optical coherence tomography angiography-guided photodynamic therapy for extrafoveal choroidal neovascularization

Digit J Ophthalmol. 2020 Mar 31;26(1):1-7. doi: 10.5693/djo.02.2020.01.001. eCollection 2020 Jan.

Abstract

Type 1 extrafoveal choroidal neovascularization (CNV) secondary to neovascular age-related macular degeneration was diagnosed in a 68-year-old woman using optical coherence tomography angiography (OCT-A) alone. The entire network of vessels was clearly visible on a 12 × 12 mm OCT-A scan segmented below the retinal pigment epithelium. The patient was initially treated with intravitreal ranibizumab followed by photodynamic therapy (PDT) guided by OCT-A. Complete resolution of subretinal fluid with shrinkage of the neovascular complex was noted 1 month after PDT.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Angiogenesis Inhibitors / therapeutic use
  • Choroidal Neovascularization / diagnostic imaging
  • Choroidal Neovascularization / drug therapy*
  • Drug Therapy, Combination
  • Female
  • Fluorescein Angiography*
  • Fovea Centralis
  • Humans
  • Intravitreal Injections
  • Photochemotherapy*
  • Photosensitizing Agents / therapeutic use*
  • Ranibizumab / therapeutic use
  • Subretinal Fluid
  • Tomography, Optical Coherence*
  • Vascular Endothelial Growth Factor A / antagonists & inhibitors
  • Wet Macular Degeneration / diagnostic imaging
  • Wet Macular Degeneration / drug therapy*

Substances

  • Angiogenesis Inhibitors
  • Photosensitizing Agents
  • VEGFA protein, human
  • Vascular Endothelial Growth Factor A
  • Ranibizumab