Where's Waldo: Identifying DCs within Mononuclear Phagocytes during Inflammation

Roxane Tussiwand; Patrick F Rodrigues

doi:10.1016/j.immuni.2020.05.006

Where's Waldo: Identifying DCs within Mononuclear Phagocytes during Inflammation

Immunity. 2020 Jun 16;52(6):892-894. doi: 10.1016/j.immuni.2020.05.006.

Authors

Roxane Tussiwand¹, Patrick F Rodrigues²

Affiliations

¹ Department of Biomedicine, University of Basel, 4058 Basel, Switzerland; National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: [email protected].
² Department of Biomedicine, University of Basel, 4058 Basel, Switzerland.

PMID: 32553175
DOI: 10.1016/j.immuni.2020.05.006

Abstract

Dendritic cells (DCs) are antigen-presenting cells subdivided in specialized subsets. In this issue, Bosteels et al. challenge this concept, identifying a unique subset of inflammatory DCs characterized by hybrid myeloid features, capable of efficiently priming CD4⁺ as well as CD8⁺ T cells.

Published by Elsevier Inc.

Publication types

Comment

MeSH terms

CD8-Positive T-Lymphocytes
Dendritic Cells
Diabetes Mellitus, Type 2*
Humans
Inflammation
Macrophages
Virus Diseases*