Quantitative Autofluorescence Following Gene Therapy With Voretigene Neparvovec

JAMA Ophthalmol. 2020 Aug 1;138(8):919-921. doi: 10.1001/jamaophthalmol.2020.2018.

Authors

Sarah R Levi¹, Jin Kyun Oh¹, Jose Ronaldo Lima de Carvalho Jr^{1

2}, Vinit B Mahajan³, Stephen H Tsang^{1

4}, Janet R Sparrow^{1

4}

Affiliations

¹ Department of Ophthalmology, Columbia University Irving Medical Center, New York, New York.
² Department of Ophthalmology, Hospital das Clínicas de Pernambuco, Empresa Brasileira de Serviços Hospitalares, Federal University of Pernambuco, Recife, Pernambuco, Brazil.
³ Byers Eye Institute, Stanford University, Palo Alto, California.
⁴ Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York.

No abstract available

Publication types

Case Reports
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Atrophy
Child
Dependovirus / genetics
Female
Genetic Therapy*
Genetic Vectors / genetics
Humans
Optical Imaging*
Retinal Dystrophies / diagnostic imaging
Retinal Dystrophies / physiopathology
Retinal Dystrophies / therapy*
Retinal Pigment Epithelium / diagnostic imaging
Retinal Pigment Epithelium / pathology*
Tomography, Optical Coherence
Visual Acuity / physiology
cis-trans-Isomerases / genetics*

Substances

retinoid isomerohydrolase
cis-trans-Isomerases

Grants and funding