Pediatric cancer research: Surviving COVID-19

Pediatr Blood Cancer. 2020 Sep;67(9):e28435. doi: 10.1002/pbc.28435. Epub 2020 Jun 18.

Abstract

A diverse panel of pediatric cancer advocates and experts, whose collective experience spans the continuum of international academic medicine, industry, government research, and cancer advocacy, recently discussed challenges for pediatric cancer research in the context of coronavirus disease 2019 (COVID-19). Specifically, this special report addresses the following focus areas: (a) the critical role that translational research has played in transforming pediatric cancer outcomes; (b) the current and potential future impact of COVID-19 on pediatric cancer research; (c) target areas of COVID-19 research that may have application in immunity, oncogenesis, and therapeutic discovery; and (d) future considerations and directions in maintaining pediatric cancer research during and after COVID-19.

Keywords: COVID-19; advocacy; cancer; coronavirus; inflammation; pediatrics; relapse; research; systemic acute respiratory syndrome; tumor.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Betacoronavirus / metabolism*
  • COVID-19
  • Child
  • Child, Preschool
  • Coronavirus Infections* / epidemiology
  • Coronavirus Infections* / metabolism
  • Coronavirus Infections* / pathology
  • Coronavirus Infections* / therapy
  • Female
  • Humans
  • Infant
  • Male
  • Neoplasms* / epidemiology
  • Neoplasms* / metabolism
  • Neoplasms* / pathology
  • Neoplasms* / therapy
  • Pandemics*
  • Pneumonia, Viral* / epidemiology
  • Pneumonia, Viral* / metabolism
  • Pneumonia, Viral* / pathology
  • Pneumonia, Viral* / therapy
  • SARS-CoV-2
  • Translational Research, Biomedical*