Prothrombotic state induced by COVID-19 infection as trigger for stroke in young patients: A dangerous association

Francesco Cavallieri; Alessandro Marti; Antonio Fasano; Annalisa Dalla Salda; Angelo Ghirarduzzi; Claudio Moratti; Lara Bonacini; Reza Ghadirpour; Rosario Pascarella; Franco Valzania; Marialuisa Zedde

doi:10.1016/j.ensci.2020.100247

Prothrombotic state induced by COVID-19 infection as trigger for stroke in young patients: A dangerous association

eNeurologicalSci. 2020 Jun 6:20:100247. doi: 10.1016/j.ensci.2020.100247. eCollection 2020 Sep.

Authors

Affiliations

¹ Neurology Unit, Neuromotor & Rehabilitation Department, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
² Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Italy.
³ Angiology Unit, Department of Internal Medicine, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
⁴ Neuroradiology Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
⁵ Neurosurgery Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.

Abstract

•COVID-19 infection could led to a pro-inflammatory and pro-thrombotic state.•Cerebrovascular involvement may occur in COVID-19 infection even in young patients.•Physicians should be aware that stroke may be the first COVID-19 manifestation.

Keywords: COVID-19; Coronavirus; Prothrombotic state; Stroke; Vertebrobasilar disease.