Current Status of Dyslipidemia Treatment for Stroke Prevention

Curr Neurol Neurosci Rep. 2020 Jun 22;20(8):31. doi: 10.1007/s11910-020-01052-4.

Abstract

Purpose of review: Elevated cholesterol is an established risk factor for ischemic stroke. The value of statins for stroke prevention has been clear for more than a decade.

Recent findings: However, the use of new medication combinations such as ezetimibe or proprotein convertase subtilisin-kexin type 9 inhibitors plus statins is increasing and the value for reducing stroke has been shown for these combination therapies. Recent data also support the strategy of lowering triglycerides for stroke prevention. A modern approach to dyslipidemia treatment and its relation to stroke prevention is summarized in this paper.

Keywords: Cholesterol; Low-density lipoprotein; Statins; Stroke; Triglycerides.

Publication types

  • Review

MeSH terms

  • Anticholesteremic Agents*
  • Cholesterol, LDL
  • Dyslipidemias* / complications
  • Dyslipidemias* / drug therapy
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors* / therapeutic use
  • Stroke* / drug therapy
  • Stroke* / prevention & control

Substances

  • Anticholesteremic Agents
  • Cholesterol, LDL
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors