Mapping the Uncharted Territories of Human Brain Malignancies

Daan Juri Kloosterman; Leila Akkari

doi:10.1016/j.cell.2020.06.003

Mapping the Uncharted Territories of Human Brain Malignancies

Cell. 2020 Jun 25;181(7):1454-1457. doi: 10.1016/j.cell.2020.06.003.

Authors

Daan Juri Kloosterman¹, Leila Akkari²

Affiliations

¹ Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Oncode Institute, Amsterdam 1066CX, the Netherlands.
² Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Oncode Institute, Amsterdam 1066CX, the Netherlands. Electronic address: [email protected].

PMID: 32589956
DOI: 10.1016/j.cell.2020.06.003

Abstract

Despite its success in multiple tumor types, immunotherapy remains poorly efficacious in brain malignancies. In this issue of Cell, Friebel et al. and Klemm et al. provide in-depth insights into the versatile nuances of immune cells in primary and metastatic brain tumors, granting the field with a rich framework to explore novel therapeutic avenues.

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MeSH terms

Brain Neoplasms* / therapy
Humans
Immunotherapy