Effect of emicizumab on thrombin generation: A case report of breakthrough bleeding during emicizumab treatment

Haemophilia. 2020 Nov;26(6):e327-e330. doi: 10.1111/hae.14085. Epub 2020 Jun 28.

Authors

Lars L F G Valke^{1

2}, Erik A M Beckers^{2

3}, Nicole M A Blijlevens¹, Waander L van Heerde^{1

2

4}, Saskia E M Schols^{1

2}

Affiliations

¹ Department of Haematology, Radboud University Medical Centre, Nijmegen, The Netherlands.
² Haemophilia Treatment Centre, Nijmegen, The Netherlands.
³ Department of Haematology, Maastricht University Medical Centre+, Maastricht, The Netherlands.
⁴ Enzyre BV, Novio Tech Campus, Nijmegen, The Netherlands.

PMID: 32596863
DOI: 10.1111/hae.14085

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Antibodies, Bispecific / pharmacology
Antibodies, Bispecific / therapeutic use*
Antibodies, Monoclonal, Humanized / pharmacology
Antibodies, Monoclonal, Humanized / therapeutic use*
Female
Humans
Middle Aged
Thrombin / drug effects*

Substances

Antibodies, Bispecific
Antibodies, Monoclonal, Humanized
emicizumab
Thrombin