SARS-CoV-2 infection in kidney transplant recipients: Early report of five cases

Transpl Infect Dis. 2021 Feb;23(1):e13394. doi: 10.1111/tid.13394. Epub 2020 Jul 14.

Abstract

From December 2019 to March 2020, China was the epicenter of the SARS-CoV-2 infection pandemic, but from that moment on, Europe surpassed China in the number of new cases and deaths related to this novel viral respiratory infection. The emergence of this world pandemic is particularly important for solid organ transplant recipients, who might have an increased risk of mortality, not only due to their chronic immunosuppression status, but also to the cardiovascular risk that correlates with several years of chronic kidney disease. To the extent that there is still a lack of knowledge about the clinical characteristics, evolution, and prognosis of SARS-CoV-2 infection in kidney transplant recipients, we will report the first 5 cases diagnosed and followed in our transplant unit, as well as share the therapeutic strategies adopted.

Keywords: COVID-19 infection; kidney transplantation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Antimalarials / therapeutic use
  • COVID-19 / complications*
  • COVID-19 / pathology
  • COVID-19 Drug Treatment
  • Female
  • Humans
  • Hydroxychloroquine / therapeutic use
  • Kidney Transplantation*
  • Male
  • Middle Aged
  • SARS-CoV-2*
  • Steroids / administration & dosage
  • Steroids / therapeutic use
  • Transplant Recipients*

Substances

  • Anti-Bacterial Agents
  • Antimalarials
  • Steroids
  • Hydroxychloroquine