Immunohistochemical Characterization of the IL-13:IL-4 Receptor α Axis in the Skin of Adult Patients with Moderate to Severe Atopic Dermatitis and Healthy Controls

J Invest Dermatol. 2021 Feb;141(2):440-443.e4. doi: 10.1016/j.jid.2020.05.108. Epub 2020 Jun 27.
No abstract available

Publication types

  • Letter
  • Observational Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Biomarkers / analysis
  • Biomarkers / metabolism
  • Biopsy
  • Case-Control Studies
  • Dermatitis, Atopic / diagnosis*
  • Dermatitis, Atopic / immunology
  • Dermatitis, Atopic / pathology
  • Female
  • Healthy Volunteers
  • Humans
  • Immunohistochemistry
  • Interleukin-13 / analysis*
  • Interleukin-13 / metabolism
  • Interleukin-4 Receptor alpha Subunit / analysis*
  • Interleukin-4 Receptor alpha Subunit / metabolism
  • Langerhans Cells / immunology
  • Langerhans Cells / metabolism
  • Male
  • Melanocytes / immunology
  • Melanocytes / metabolism
  • Middle Aged
  • Severity of Illness Index
  • Skin / cytology
  • Skin / immunology
  • Skin / pathology*
  • Young Adult

Substances

  • Biomarkers
  • IL13 protein, human
  • IL4R protein, human
  • Interleukin-13
  • Interleukin-4 Receptor alpha Subunit