Three Cases of Diffuse, Intense Stomach Uptake on DOTATATE PET

Clin Nucl Med. 2020 Oct;45(10):813-816. doi: 10.1097/RLU.0000000000003153.

Abstract

Incidental tracer uptake on DOTATATE PET is increasingly encountered in clinical practice. We describe 3 patients with suspected or known neuroendocrine tumor who were found to have diffuse and intense stomach uptake on DOTATATE PET. All patients underwent esophagogastroduodenoscopy and/or endoscopic ultrasound; the cause of the stomach uptake was attributed to proton-pump inhibitor use, chronic gastritis, and gastrinoma, respectively. These 3 cases highlight that diffuse and intense stomach DOTATATE uptake can be a benign finding probably attributed to proton-pump inhibitor use, chronic gastritis, or gastrinoma.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Biological Transport
  • Diffusion
  • Female
  • Gastric Mucosa / metabolism*
  • Humans
  • Male
  • Middle Aged
  • Neuroendocrine Tumors / diagnostic imaging*
  • Neuroendocrine Tumors / metabolism*
  • Neuroendocrine Tumors / pathology
  • Organometallic Compounds / metabolism*
  • Positron Emission Tomography Computed Tomography*
  • Stomach / diagnostic imaging
  • Stomach / pathology

Substances

  • Organometallic Compounds