Hispanic ethnicity is associated with prolonged clearance of high dose methotrexate and severe nephrotoxicity in children and adolescents with acute lymphoblastic leukemia

Leuk Lymphoma. 2020 Nov;61(11):2771-2774. doi: 10.1080/10428194.2020.1783445. Epub 2020 Jul 1.

Authors

Dolores Mullikin^{1

2}, Daniel Ranch³, Yasmin Khalfe⁴, Brandon Lucari⁴, Mark C Zobeck^{1

2}, Chatchawin Assanasen³, M Monica Gramatges^{1

2}, Michael E Scheurer^{1

2}, Eric S Schafer^{1

2}

Affiliations

¹ Texas Children's Cancer and Hematology Centers, Houston, TX, USA.
² Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
³ Department of Pediatrics, The University of Texas Health Science Center at San Antonio, TX, USA.
⁴ School of Medicine, Baylor College of Medicine, Houston, TX, USA.

PMID: 32605405
DOI: 10.1080/10428194.2020.1783445

No abstract available

Publication types

Letter

MeSH terms

Adolescent
Child
Ethnicity
Hispanic or Latino
Humans
Infant
Methotrexate / adverse effects
Precursor Cell Lymphoblastic Leukemia-Lymphoma* / drug therapy
Renal Insufficiency*

Substances

Methotrexate