Advanced atrioventricular block in a neonate with lupus erythematosus and anti-SS-A antibodies

Pediatr Cardiol. 1988;9(2):121-4. doi: 10.1007/BF02083711.

Abstract

Recent studies suggested that the involvement of anti-SS-A and anti-SS-B antibodies in the pathogenesis of neonatal lupus erythematosus and congenital heart block. We here describe a female neonate with lupus erythematosus, advanced atrioventricular block, and a positive test for anti-SS-A antibodies. The findings of His-bundle recordings are presented.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Antinuclear / analysis*
  • Bundle of His / physiopathology
  • Electrocardiography
  • Female
  • Heart Block / congenital*
  • Heart Block / immunology
  • Heart Block / physiopathology
  • Humans
  • Infant, Newborn
  • Lupus Erythematosus, Systemic / congenital*
  • Lupus Erythematosus, Systemic / immunology

Substances

  • Antibodies, Antinuclear
  • SS-A antibodies