Evaluating the Image Quality of Monoenergetic Images From Dual-Energy Computed Tomography With Low-Concentration and Low-Flow-Rate Contrast Media for the Arterials Supply to the Nipple-Areola Complex in Breast Cancer Compared With Conventional Computed Tomography Angiography

J Comput Assist Tomogr. 2020 Nov/Dec;44(6):921-927. doi: 10.1097/RCT.0000000000001063.

Abstract

Objective: The objective of this study was to evaluate the image quality of monoenergetic images (MEIs (+)) acquired from dual-energy computed tomography with low-concentration and low-flow-rate contrast media for the arterial supply to the nipple-areola complex (NAC) in breast cancer compared with conventional computed tomography angiography (CTA).

Methods: We enrolled 25 patients (MEI (+)300 group, 300 mg/mL and 2.5 mL/s of contrast media) and 23 patients (CTA370 group, 370 mg/mL and 3.5 mL/s of contrast media) for assessing NAC blood supply angiography. The image quality of the 2 groups was evaluated objectively and subjectively.

Results: The 40 keV MEI (+)300 demonstrated higher attenuation and contrast-to-noise ratio than CTA370 group (P < 0.001). The subjective image quality and visualization of the arteries were comparable between 2 groups.

Conclusions: The 40 keV MEI (+)300 acquired from dual-energy computed tomography can achieve comparable image quality of arterial supply to NAC with low-concentration and low-flow-rate contrast media in breast cancer compared with CTA370.

Publication types

  • Comparative Study

MeSH terms

  • Breast / blood supply
  • Breast / diagnostic imaging
  • Breast Neoplasms / diagnostic imaging*
  • Computed Tomography Angiography / methods
  • Contrast Media
  • Female
  • Humans
  • Image Interpretation, Computer-Assisted / methods*
  • Middle Aged
  • Nipples / blood supply
  • Nipples / diagnostic imaging
  • Prospective Studies
  • Radiographic Image Enhancement / methods*
  • Radiography, Dual-Energy Scanned Projection / methods*
  • Reproducibility of Results
  • Signal-To-Noise Ratio
  • Tomography, X-Ray Computed / methods*

Substances

  • Contrast Media