Human Sialome and Coronavirus Disease-2019 (COVID-19) Pandemic: An Understated Correlation?

Front Immunol. 2020 Jun 23:11:1480. doi: 10.3389/fimmu.2020.01480. eCollection 2020.

Authors

Daniela Morniroli¹, Maria Lorella Giannì^{1

2}, Alessandra Consales², Carlo Pietrasanta^{1

2}, Fabio Mosca^{1

2}

Affiliations

¹ Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, NICU, Milan, Italy.
² Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.

No abstract available

Keywords: COVID-19; SARS-CoV-2; human sialome; pathogen susceptibility; sialic acid; sialoquake; viral infection.

MeSH terms

Age Factors
Aging / metabolism
Angiotensin-Converting Enzyme 2
Betacoronavirus / metabolism*
COVID-19
Coronavirus Infections / metabolism*
Coronavirus Infections / virology
Disease Susceptibility
Female
Host-Pathogen Interactions
Humans
Male
N-Acetylneuraminic Acid / metabolism*
Neuraminic Acids / metabolism*
Pandemics
Peptidyl-Dipeptidase A / metabolism
Pneumonia, Viral / metabolism*
Pneumonia, Viral / virology
Respiratory Mucosa / metabolism
SARS-CoV-2
Sex Factors
Spike Glycoprotein, Coronavirus / metabolism*

Substances

Neuraminic Acids
Spike Glycoprotein, Coronavirus
spike protein, SARS-CoV-2
N-glycolylneuraminic acid
Peptidyl-Dipeptidase A
ACE2 protein, human
Angiotensin-Converting Enzyme 2
N-Acetylneuraminic Acid