Yeast hexokinase mutants

J Biol Chem. 1977 Jul 10;252(13):4443-4.

Abstract

Using yeast mutants, it is shown that growth on glucose occurs even in the absence of both hexokinase A and hexokinase B; fructose growth requires at least one of these two enzymes. Expression of hexokinase A and of glucokinase seem to be regulated.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Culture Media
  • Fructose / pharmacology
  • Glucokinase / metabolism
  • Glucose / pharmacology
  • Hexokinase / metabolism*
  • Mutation
  • Saccharomyces cerevisiae / drug effects
  • Saccharomyces cerevisiae / enzymology*
  • Saccharomyces cerevisiae / growth & development

Substances

  • Culture Media
  • Fructose
  • Hexokinase
  • Glucokinase
  • Glucose