Impact of the COVID-19 outbreak on acute stroke care

J Neurol. 2021 Feb;268(2):403-408. doi: 10.1007/s00415-020-10069-1. Epub 2020 Jul 20.

Abstract

Background and purpose: There are concerns that the coronavirus disease 2019 (COVID-19) outbreak negatively affects the quality of care for acute cardiovascular conditions. We assessed the impact of the COVID-19 outbreak on trends in hospital admissions and workflow parameters of acute stroke care in Amsterdam, The Netherlands.

Methods: We used data from the three hospitals that provide acute stroke care for the Amsterdam region. We compared two 7-week periods: one during the peak of the COVID-19 outbreak (March 16th-May 3th 2020) and one prior to the outbreak (October 21st-December 8th 2019). We included consecutive patients who presented to the emergency departments with a suspected stroke and assessed the change in number of patients as an incidence-rate ratio (IRR) using a Poisson regression analysis. Other outcomes were the IRR for stroke subtypes, change in use of reperfusion therapy, treatment times, and in-hospital complications.

Results: During the COVID-19 period, 309 patients presented with a suspected stroke compared to 407 patients in the pre-COVID-19 period (IRR 0.76 95%CI 0.65-0.88). The proportion of men was higher during the COVID-19 period (59% vs. 47%, p < 0.001). There was no change in the proportion of stroke patients treated with intravenous thrombolysis (28% vs. 30%, p = 0.58) or endovascular thrombectomy (11% vs 12%, p = 0.82) or associated treatment times. Seven patients (all ischemic strokes) were diagnosed with COVID-19.

Conclusion: We observed a 24% decrease in suspected stroke presentations during the COVID-19 outbreak, but no evidence for a decrease in quality of acute stroke care.

Keywords: Acute care; Quality; Reperfusion; Stroke.

MeSH terms

  • Aged
  • Aged, 80 and over
  • COVID-19* / epidemiology
  • Emergency Medical Services
  • Female
  • Hospitalization
  • Humans
  • Incidence
  • Ischemic Stroke / complications
  • Ischemic Stroke / epidemiology
  • Male
  • Middle Aged
  • Netherlands / epidemiology
  • Pandemics*
  • Poisson Distribution
  • Quality of Health Care
  • Reperfusion
  • Retrospective Studies
  • Stroke / complications
  • Stroke / epidemiology
  • Stroke / therapy*
  • Thrombectomy / statistics & numerical data
  • Thrombolytic Therapy / statistics & numerical data
  • Time-to-Treatment
  • Treatment Outcome