Mapping Robust Genetic Variants Associated with Exercise Responses

Int J Sports Med. 2021 Jan;42(1):3-18. doi: 10.1055/a-1198-5496. Epub 2020 Jul 21.

Abstract

This review summarised robust and consistent genetic variants associated with aerobic-related and resistance-related phenotypes. In total we highlight 12 SNPs and 7 SNPs that are robustly associated with variance in aerobic-related and resistance-related phenotypes respectively. To date, there is very little literature ascribed to understanding the interplay between genes and environmental factors and the development of physiological traits. We discuss future directions, including large-scale exercise studies to elucidate the functional relevance of the discovered genomic markers. This approach will allow more rigour and reproducible research in the field of exercise genomics.

Publication types

  • Review

MeSH terms

  • Endurance Training*
  • Genetic Markers
  • Humans
  • Phenotype
  • Polymorphism, Single Nucleotide / physiology*
  • Resistance Training*

Substances

  • Genetic Markers