MPN patients with low mutant JAK2 allele burden show late expansion restricted to erythroid and megakaryocytic lineages

Blood. 2020 Nov 26;136(22):2591-2595. doi: 10.1182/blood.2019002943.

Authors

Affiliations

¹ Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland.
² Institute of Integrative Biology, Eidgenössische Technische Hochschule (ETH) Zürich, Zürich, Switzerland.
³ Division of Hematology, University Hospital Basel, Basel, Switzerland.
⁴ Clinic of Hematology, Clinical Center of Serbia, Belgrade, Serbia; and.
⁵ Institute for Medical Research, University of Belgrade, Belgrade, Serbia.

PMID: 32698197
DOI: 10.1182/blood.2019002943

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Alleles*
Amino Acid Substitution
Erythroid Cells* / metabolism
Erythroid Cells* / pathology
Female
Humans
Janus Kinase 2* / genetics
Janus Kinase 2* / metabolism
Male
Megakaryocytes* / metabolism
Megakaryocytes* / pathology
Mutation, Missense*
Myeloproliferative Disorders* / genetics
Myeloproliferative Disorders* / metabolism
Myeloproliferative Disorders* / pathology

Substances

JAK2 protein, human
Janus Kinase 2