Tibiotalocalcaneal Fusion With Antibiotic Cement-Coated Nails for Refractory Deep Infection After Ankle ORIF

Foot Ankle Int. 2020 Nov;41(11):1391-1397. doi: 10.1177/1071100720939884. Epub 2020 Jul 25.

Abstract

Background: Deep infection after open reduction internal fixation (ORIF) of ankle fractures represents a challenge to the orthopaedic surgeon, particularly in patients in whom conventional surgical treatments have failed. The aim of this study was to assess the results of a modified technique of tibiotalocalcaneal fusion using a retrograde locked intramedullary nail covered in cement with antibiotics.

Methods: Six patients treated using the authors' technique were analyzed retrospectively. All patients had deep infection after ankle osteosynthesis and several surgical procedures (debridement, external fixation, etc) had failed. Radiographs were analyzed to confirm the healing of the bone. Outcome was measured by maintained construct stability and eradication of infection (no clinical signs of infection and normal values of laboratory markers). The average age of the series was 64.2 (range, 50-75) years, and the average follow-up period was 19.5 (range, 8-41) months.

Results: Tibiotalocalcaneal stability and eradication of the infection were achieved in all patients, along with the normalization of clinical and radiologic parameters. In the patient who underwent a talectomy, one of the calcaneal locking screws broke, with no clinical repercussions.

Conclusion: Tibiotalocalcaneal fusion with antibiotic cement-coated retrograde nails was useful in providing clinically acceptable results in the control of chronic infection in complex patients after the failure of previous surgeries.

Level of evidence: Level IV, therapeutic study.

Keywords: ankle fracture; antibiotic cement; intramedullary nail; osteomyelitis; tibiotalocalcaneal fusion.

MeSH terms

  • Aged
  • Ankle Fractures / surgery*
  • Anti-Bacterial Agents / therapeutic use*
  • Arthrodesis / methods*
  • Bone Cements*
  • Bone Nails*
  • Coated Materials, Biocompatible
  • Female
  • Fracture Fixation, Intramedullary / methods
  • Humans
  • Male
  • Middle Aged
  • Postoperative Complications / drug therapy
  • Postoperative Complications / surgery
  • Prosthesis-Related Infections / drug therapy*
  • Prosthesis-Related Infections / surgery*
  • Reoperation / methods
  • Retrospective Studies

Substances

  • Anti-Bacterial Agents
  • Bone Cements
  • Coated Materials, Biocompatible