Update on the COVID-19-associated inflammatory syndrome in children and adolescents; paediatric inflammatory multisystem syndrome-temporally associated with SARS-CoV-2

Davinder Singh-Grewal; Ryan Lucas; Kristine McCarthy; Allen C Cheng; Nicholas Wood; Genevieve Ostring; Philip Britton; Nigel Crawford; David Burgner

doi:10.1111/jpc.15049

Update on the COVID-19-associated inflammatory syndrome in children and adolescents; paediatric inflammatory multisystem syndrome-temporally associated with SARS-CoV-2

J Paediatr Child Health. 2020 Aug;56(8):1173-1177. doi: 10.1111/jpc.15049. Epub 2020 Jul 31.

Authors

Davinder Singh-Grewal^{1

2

3

4}, Ryan Lucas^{1

2}, Kristine McCarthy^{1

2}, Allen C Cheng^{5

6}, Nicholas Wood^{1

2}, Genevieve Ostring^{7

8}, Philip Britton^{1

2}, Nigel Crawford^{9

10

11}, David Burgner^{9

12

13

14}

Affiliations

¹ Department of Rheumatology, The Sydney Children's Hospitals Network, Sydney, New South Wales, Australia.
² Paediatrics and Child Health, The University of Sydney, Sydney, New South Wales, Australia.
³ School of Maternal and Child Health, University of New South Wales, Sydney, New South Wales, Australia.
⁴ Department of Paediatrics, John Hunter Children's Hospital, Newcastle, New South Wales, Australia.
⁵ Department of Infectious Diseases, Alfred Health, Melbourne, Victoria, Australia.
⁶ School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
⁷ Paediatric Rheumatology, Starship Children's Hospital, Auckland, New Zealand.
⁸ University of Auckland, Paediatrics Child and Youth Health, Auckland, New Zealand.
⁹ Infection and Immunity, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.
¹⁰ Immunisation Service, Royal Children's Hospital, Melbourne, Victoria, Australia.
¹¹ University of Melbourne, Melbourne, Victoria, Australia.
¹² Infectious Diseases University, Royal Children's Hospital, Melbourne, Victoria, Australia.
¹³ Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.
¹⁴ Department of Paediatrics, Monash University, Melbourne, Victoria, Australia.

Abstract

We provide an update on the state of play with regards a newly described inflammatory condition which has arisen during the current SARS-CoV-2 pandemic. The condition has been named paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 or multisystem inflammatory syndrome in children. This condition has shown significant similarities to Kawasaki disease and toxic shock syndrome.

Publication types

Comment

MeSH terms

Adolescent
Betacoronavirus*
COVID-19
Child
Coronavirus Infections*
Humans
Pandemics*
Pneumonia, Viral*
SARS-CoV-2