Aggressive surgery for advanced ovarian cancer performed by a multidisciplinary team: A retrospective analysis on a large series of patients

Stefano Rausei; Stefano Uccella; Valentina D'Alessandro; Baldo Gisone; Francesco Frattini; Georgios Lianos; Francesca Rovera; Luigi Boni; Gianlorenzo Dionigi; Fabio Ghezzi

doi:10.1016/j.sopen.2019.05.005

Aggressive surgery for advanced ovarian cancer performed by a multidisciplinary team: A retrospective analysis on a large series of patients

Surg Open Sci. 2019 Jun 30;1(1):43-47. doi: 10.1016/j.sopen.2019.05.005. eCollection 2019 Jul.

Authors

Affiliations

¹ Department of Surgery, ASST Valle Olona, Gallarate (VA), Italy.
² Department of Obstetrics and Gynecology, Ospedale degli Infermi, Biella, Italy.
³ Department of Gynecology, ASST Settelaghi, University of Insubria, Varese, Italy.
⁴ Department of Surgery, ASST Settelaghi, University of Insubria, Varese, Italy.
⁵ Department of Surgery, Ioannina, Greece.
⁶ Department of Surgery, IRCCS Ca' Granda - Policlinico Hospital, University of Milan, Milan, Italy.
⁷ Department of Human Pathology in Adulthood and Childhood, University of Messina, Messina, Italy.

Abstract

Background: To evaluate the impact of extended surgical treatment performed by a team of gynecologists and general surgeons on postoperative morbidity and survival of patients with advanced ovarian cancer.

Methods: We collected data of 156 patients with advanced ovarian cancer stage IIb-III-IV according to International Federation of Gynecology and Obstetrics classification and treated with primary cytoreduction. End points were perioperative and postoperative complications and cancer-related survival.

Results: In 51 cases (51/156, 32.7%) a multivisceral resection was completed. Postoperative complications occurred in 52 cases (33.3%). The duration of the surgical procedure as well as the need for diaphragmatic peritonectomy were the factors independently associated with the development of postoperative complications. Five-year cancer-related survival rate was of 50.7%: only histotype and residual tumor resulted significantly associated.

Conclusions: Our results highlight the importance of a team of gynecologists and general surgeons with specific interests and skills to achieve cytoreduction as rapidly as possible, even when it implies very complex maneuvers.