Shared clonal IGH rearrangement in BCP-ALL occurring after CLL: pitfalls and implications for MRD monitoring

Br J Haematol. 2020 Nov;191(3):506-509. doi: 10.1111/bjh.17008. Epub 2020 Aug 5.
No abstract available

Keywords: BCP-ALL; CLL; clonal relationship; therapy-related.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Biomarkers, Tumor
  • Biopsy
  • Bone Marrow / metabolism
  • Chromosome Aberrations
  • Clonal Evolution / genetics*
  • Disease Progression
  • Female
  • Gene Rearrangement*
  • High-Throughput Nucleotide Sequencing
  • Humans
  • Immunoglobulin Heavy Chains / genetics*
  • Immunophenotyping / methods
  • Leukemia, Lymphocytic, Chronic, B-Cell / genetics*
  • Leukemia, Lymphocytic, Chronic, B-Cell / pathology*
  • Middle Aged
  • Neoplasm, Residual / diagnosis
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / diagnosis*
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / genetics*

Substances

  • Biomarkers, Tumor
  • Immunoglobulin Heavy Chains