Molecular Crux of Hair Cell Mechanotransduction Machinery

Umar Al-Sheikh; Lijun Kang

doi:10.1016/j.neuron.2020.07.007

Molecular Crux of Hair Cell Mechanotransduction Machinery

Neuron. 2020 Aug 5;107(3):404-406. doi: 10.1016/j.neuron.2020.07.007.

Authors

Umar Al-Sheikh¹, Lijun Kang²

Affiliations

¹ Department of Neurobiology and Department of Neurosurgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310053, China; NHC and CAMS Key Laboratory of Medical Neurobiology, MOE Frontier Science Center for Brain Research and Brain-Machine Integration, School of Brain Science and Brain Medicine, Zhejiang University, Hangzhou, Zhejiang 310053, China.
² Department of Neurobiology and Department of Neurosurgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310053, China; NHC and CAMS Key Laboratory of Medical Neurobiology, MOE Frontier Science Center for Brain Research and Brain-Machine Integration, School of Brain Science and Brain Medicine, Zhejiang University, Hangzhou, Zhejiang 310053, China. Electronic address: [email protected].

PMID: 32758446
DOI: 10.1016/j.neuron.2020.07.007

Abstract

Although 62 years have elapsed since the first report of hereditary deafness in a mouse strain, the molecular mechanism of hair cell mechanotransduction remains elusive. Three recent studies present crucial insights into the molecular crux of hair cell mechanotransduction machinery.

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MeSH terms

Animals
Hair Cells, Auditory*
Mechanotransduction, Cellular*
Mice