Two Cases of SARS-CoV-2 Infection in Pediatric Oncohematologic Patients in Spain

Pediatr Infect Dis J. 2020 Nov;39(11):1040-1042. doi: 10.1097/INF.0000000000002841.

Abstract

Since December 2019, severe acute respiratory syndrome coronavirus 2 infection has spread worldwide. We all are concerned about immunocompromised children, especially hematologic and oncologic pediatric patients. We want to share our experience with 2 pediatric cancer patients with severe acute respiratory syndrome coronavirus 2 infection. Both presented mild disease and good outcome. No respiratory symptoms were identified, but both developed diarrhea, one probably secondary to lopinavir/ritonavir. Pediatric cancer patients may have milder disease than adults, but larger studies are needed to make conclusions.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Betacoronavirus / isolation & purification
  • COVID-19
  • Child
  • Child, Preschool
  • Coronavirus Infections / diagnosis*
  • Coronavirus Infections / drug therapy
  • Coronavirus Infections / epidemiology
  • Diarrhea / etiology
  • Diarrhea / virology
  • Female
  • Humans
  • Kidney Neoplasms / epidemiology
  • Kidney Neoplasms / virology*
  • Lopinavir / therapeutic use
  • Pandemics
  • Pneumonia, Viral / diagnosis*
  • Pneumonia, Viral / drug therapy
  • Pneumonia, Viral / epidemiology
  • Ritonavir / therapeutic use
  • SARS-CoV-2
  • Sarcoma, Ewing / epidemiology
  • Sarcoma, Ewing / virology*
  • Spain / epidemiology
  • Wilms Tumor / epidemiology
  • Wilms Tumor / virology*

Substances

  • Lopinavir
  • Ritonavir