[Research progress on the correlation between nasal sinus microbiome and chronic rhinosinusitis]

K J Wang; C J Yu; X Gao

doi:10.3760/cma.j.cn115330-20200303-00152

[Research progress on the correlation between nasal sinus microbiome and chronic rhinosinusitis]

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Aug 7;55(8):803-808. doi: 10.3760/cma.j.cn115330-20200303-00152.

[Article in Chinese]

Authors

K J Wang¹, C J Yu², X Gao²

Affiliations

¹ Department of Otolaryngology Head and Neck Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing 210008, China.
² Department of Otolaryngology Head and Neck Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing 210008, China; Department of Otolaryngology Head and Neck Surgery, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Jiangsu Provincial Key Medical Discipline, Nanjing 210008, China; Research Institute of Otolaryngology, Nanjing Drum Tower Hospital, Nanjing 210008, China.

PMID: 32791785
DOI: 10.3760/cma.j.cn115330-20200303-00152

Abstract

慢性鼻窦炎（chronic rhinosinusitis, CRS）是耳鼻咽喉科常见病之一。目前CRS病因尚未研究清楚，鼻腔鼻窦微生物组（microbiome）在CRS中的潜在作用也在争论中。近年来，随着现代分子检测技术的发展，提高了人们对鼻腔鼻窦微生物组的认识。最近的研究利用二代测序技术更全面地认识了CRS的微生物组的复杂性。本文综述了目前对细菌、真菌和病毒与CRS相关性的研究，介绍了二代测序技术应用于CRS的微生物组研究，探讨了微生物组与CRS的可能致病机制及CRS微生物疗法的可能性。.

MeSH terms

Biomedical Research
Chronic Disease
Humans
Microbiota*
Nasal Polyps*
Paranasal Sinuses* / microbiology
Rhinitis* / microbiology
Sinusitis* / microbiology

Abstract

MeSH terms

Grants and funding