Differential activity of glucocerebrosidase in neurons and astrocytes; implications for evaluating tissue homogenates derived from Parkinson's disease brains

J Neurol Sci. 2020 Nov 15:418:117097. doi: 10.1016/j.jns.2020.117097. Epub 2020 Aug 13.

Authors

Derek Burke¹, Simon Heales²

Affiliations

¹ Enzyme Unit, NIHR BRC Great Ormond Street Hospital Foundation Trust and UCL Great Ormond Street Institute of Child Health, London, UK.
² Enzyme Unit, NIHR BRC Great Ormond Street Hospital Foundation Trust and UCL Great Ormond Street Institute of Child Health, London, UK. Electronic address: [email protected].

PMID: 32823133
DOI: 10.1016/j.jns.2020.117097

No abstract available

Keywords: Astrocytes; Glucocerebrosidase; Neurons; Parkinson’s.

Publication types

Letter

MeSH terms

Astrocytes
Glucosylceramidase* / genetics
Humans
Neurons
Parkinson Disease*
alpha-Synuclein

Substances

alpha-Synuclein
Glucosylceramidase