Endovascular Recanalization for Nonacute Intracranial Vertebral Artery Occlusion According to a New Classification

Stroke. 2020 Nov;51(11):3340-3343. doi: 10.1161/STROKEAHA.120.030440. Epub 2020 Aug 25.

Abstract

Background and purpose: Endovascular recanalization for patients with nonacute intracranial vertebral artery occlusion remains clinically challenging. We aim to evaluate the feasibility and safety of endovascular recanalization for nonacute intracranial vertebral artery occlusion and propose a new angiographic classification.

Methods: Fifty patients with symptomatic atherosclerotic nonacute intracranial vertebral artery occlusion from January 2015 to December 2019 were analyzed, retrospectively. The rate of recanalization, peri-procedural complications, and follow-up results were evaluated. All patients were divided into 4 groups according to an angiographic classification.

Results: Among the 50 patients, 38 (76%) achieved successful recanalization. Any stroke or death within 30 days was 4% (2/50). From type I to type IV, the recanalization rate gradually decreased (94.1%, 76.9%, 70%, and 50%, respectively, P=0.012), while the perioperative complication rate gradually increased (0.0%, 7.7%, 20%, and 50%, respectively, P=0.001).

Conclusions: Endovascular recanalization may be feasible and safe for carefully selected patients with symptomatic atherosclerotic nonacute intracranial vertebral artery occlusion and, therefore, represents an alternative treatment, especially for type I and type II patients.

Keywords: heparin; intracranial aneurysm; risk factor; transient ischemic attack; vertebral artery.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Angiography, Digital Subtraction
  • Angioplasty, Balloon / methods*
  • Cerebral Angiography
  • Computed Tomography Angiography
  • Dual Anti-Platelet Therapy
  • Endovascular Procedures / methods*
  • Feasibility Studies
  • Female
  • Humans
  • Ischemic Attack, Transient / etiology
  • Ischemic Attack, Transient / surgery
  • Magnetic Resonance Angiography
  • Male
  • Middle Aged
  • Mortality
  • Postoperative Complications / epidemiology
  • Retrospective Studies
  • Stents
  • Stroke / epidemiology
  • Treatment Outcome
  • Vertebral Artery / surgery*
  • Vertebrobasilar Insufficiency / classification
  • Vertebrobasilar Insufficiency / complications
  • Vertebrobasilar Insufficiency / diagnostic imaging
  • Vertebrobasilar Insufficiency / surgery*