African swine fever whole-genome sequencing-Quantity wanted but quality needed

PLoS Pathog. 2020 Aug 27;16(8):e1008779. doi: 10.1371/journal.ppat.1008779. eCollection 2020 Aug.

Abstract

The pandemic spread of African swine fever virus (ASFV) genotype II (GTII) has led to a global crisis. Since the circulating strains are almost identical, time and money have been mis-invested in whole-genome sequencing the last years. New methods, harmonised protocols for sample selection, sequencing, and bioinformatics are therefore urgently needed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • African Swine Fever / diagnosis*
  • African Swine Fever / virology
  • African Swine Fever Virus / classification*
  • African Swine Fever Virus / genetics*
  • African Swine Fever Virus / isolation & purification
  • Animals
  • Computational Biology / methods
  • Genes, Viral / genetics*
  • Genetic Variation*
  • Genome, Viral*
  • Genotype
  • High-Throughput Nucleotide Sequencing / methods
  • Phylogeny
  • Quality Control
  • Swine
  • Whole Genome Sequencing / methods*

Grants and funding

This study was funded intramurally through the “FLI’s ASFV-Research-Network.” The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.