Universal Shelter-in-Place Versus Advanced Automated Contact Tracing and Targeted Isolation: A Case for 21st-Century Technologies for SARS-CoV-2 and Future Pandemics

Mayo Clin Proc. 2020 Sep;95(9):1898-1905. doi: 10.1016/j.mayocp.2020.06.027. Epub 2020 Jun 22.

Abstract

Objective: To model and compare effect of digital contact tracing versus shelter-in-place on severe acute respiratory syndrome - coronavirus 2 (SARS-CoV-2) spread.

Methods: Using a classical epidemiologic framework and parameters estimated from literature published between February 1, 2020, and May 25, 2020, we modeled two non-pharmacologic interventions - shelter-in-place and digital contact tracing - to curb spread of SARS-CoV-2. For contact tracing, we assumed an advanced automated contact tracing (AACT) application that sends alerts to individuals advising self-isolation based on individual exposure profile. Model parameters included percentage population ordered to shelter-in-place, adoption rate of AACT, and percentage individuals who appropriately follow recommendations. Under influence of these variables, the number of individuals infected, exposed, and isolated were estimated.

Results: Without any intervention, a high rate of infection (>10 million) with early peak is predicted. Shelter-in-place results in rapid decline in infection rate at the expense of impacting a large population segment. The AACT model achieves reduction in infected and exposed individuals similar to shelter-in-place without impacting a large number of individuals. For example, a 50% AACT adoption rate mimics a shelter-in-place order for 40% of the population and results in a greater than 90% decrease in peak number of infections. However, as compared to shelter-in-place, with AACT significantly fewer individuals would be isolated.

Conclusion: Wide adoption of digital contact tracing can mitigate infection spread similar to universal shelter-in-place, but with considerably fewer individuals isolated.

MeSH terms

  • Automation
  • Betacoronavirus
  • COVID-19
  • Communicable Disease Control / methods*
  • Contact Tracing / methods*
  • Coronavirus Infections / prevention & control*
  • Coronavirus Infections / transmission
  • Humans
  • Models, Theoretical
  • Pandemics / prevention & control*
  • Pneumonia, Viral / prevention & control*
  • Pneumonia, Viral / transmission
  • SARS-CoV-2
  • Social Isolation
  • Software*