COVID-19 prevention and treatment: A critical analysis of chloroquine and hydroxychloroquine clinical pharmacology

PLoS Med. 2020 Sep 3;17(9):e1003252. doi: 10.1371/journal.pmed.1003252. eCollection 2020 Sep.

Nicholas J White^{1

2}, James A Watson^{1

2}, Richard M Hoglund^{1

2}, Xin Hui S Chan^{1

2

3}, Phaik Yeong Cheah^{1

2}, Joel Tarning^{1

2}

¹ Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
² Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
³ Hospital for Tropical Diseases, University College London Hospitals NHS Foundation Trust, London, United Kingdom.

Abstract

Nicholas White and coauthors discuss chloroquine and hydroxychloroquine pharmacology in the context of possible treatment of SARS-CoV-2 infection.

The authors received no specific funding for this work.