Abstract
A double-blind parallel multi-centre study of 102 patients with rheumatoid arthritis (RA) was performed, comparing ibuprofen (1200-2400 mg daily) and ketoprofen (150-300 mg daily) a new non-steroidal, anti-inflammatory agent, over a three month period. Ketoprofen was well tolerated and shown to have comparable efficacy with ibuprofen. Longterm efficacy and tolerance studies are indicated.
Publication types
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Clinical Trial
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Comparative Study
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Controlled Clinical Trial
MeSH terms
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Adult
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Aged
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Arthritis, Rheumatoid / drug therapy*
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Benzophenones / therapeutic use*
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Clinical Trials as Topic
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Drug Evaluation
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Female
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Humans
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Ibuprofen / administration & dosage
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Ibuprofen / adverse effects
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Ibuprofen / therapeutic use*
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Ketoprofen / administration & dosage
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Ketoprofen / adverse effects
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Ketoprofen / therapeutic use*
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Male
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Middle Aged
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Phenylpropionates / therapeutic use*
Substances
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Benzophenones
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Phenylpropionates
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Ketoprofen
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Ibuprofen