High anxiety and health-related quality of life in families with children with food allergy during coronavirus disease 2019

Ann Allergy Asthma Immunol. 2021 Jan;126(1):83-88.e1. doi: 10.1016/j.anai.2020.09.010. Epub 2020 Sep 18.

Abstract

Background: Food allergy has a known effect on quality of life (QoL), but this has not been extensively studied during the coronavirus disease 2019 pandemic.

Objective: To characterize the levels of anxiety of mothers of children aged 0 to 8 years with food allergy compared with families of children without a food allergy and the health-related QoL among children with food allergy during the coronavirus disease 2019 pandemic.

Methods: In a mixed-methods study, Canadian mothers of children aged 0 to 8 years with (cases) and without (controls) food allergy provided demographic data and completed age-appropriate anxiety questionnaires between April 14, 2020, and April 28, 2020. The cases also provided food allergy-related data and completed the Food Allergy Quality of Life Questionnaire. In-depth interviews were subsequently conducted with purposefully selected cases.

Results: In a total of 580 participants, 5.5% were cases and 94.5% were controls. For mothers of children aged 0 to 1.5 years, anxiety levels did not differ between cases and controls. For mothers of children aged 1.5 to 8 years, anxiety levels were higher in cases vs controls (P < .05). Among the cases, neither overall nor domain-specific Food Allergy Quality of Life Questionnaire scores differed between age groups (0-3 vs 4-7 years), even after adjustment for confounding variables, including childcare during the pandemic. Qualitatively, the following 3 themes were identified: unexpected challenges of food shopping; less food-related food anxiety during the pandemic; and differences and delays in food allergy testing and therapy.

Conclusion: Mothers of children with food allergy reported high anxiety and poor health-related QoL. Yet, qualitatively, day-to-day food allergy management was better during the pandemic.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anxiety / diagnosis
  • Anxiety / etiology
  • Anxiety / immunology
  • Anxiety / psychology*
  • COVID-19 / epidemiology*
  • COVID-19 / immunology
  • COVID-19 / psychology
  • COVID-19 / virology
  • Canada / epidemiology
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Female
  • Food Hypersensitivity / complications
  • Food Hypersensitivity / diagnosis
  • Food Hypersensitivity / immunology
  • Food Hypersensitivity / psychology*
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Mothers / psychology
  • Pandemics*
  • Quality of Life / psychology*
  • SARS-CoV-2 / pathogenicity
  • Surveys and Questionnaires