Abstract
Pre-extensively drug resistant tuberculosis (pre-XDR-TB) has been an area of growing concern, and posing a threat to global efforts of TB control. We report a case of PreXDR-TB spondylodiscitis with resistance to a Fluoroquinolone, in an immunocompetent patient under antibacillary treatment for pleural tuberculosis, managed with drug sensitivity-based second-line antituberculous drug regimen. Our case shows the challenges of the diagnostic and management of Drug-resistant TB spondylodiscitis.
Keywords:
Tuberculosis; drug-resistance; second-line treatment; spondylodiscitis.
Copyright: Safaa Fellous et al.
MeSH terms
-
Adult
-
Antitubercular Agents / pharmacology*
-
Discitis / diagnosis
-
Discitis / drug therapy*
-
Discitis / microbiology
-
Drug Resistance, Multiple, Bacterial
-
Extensively Drug-Resistant Tuberculosis / diagnosis
-
Extensively Drug-Resistant Tuberculosis / drug therapy*
-
Extensively Drug-Resistant Tuberculosis / microbiology
-
Fluoroquinolones / pharmacology
-
Humans
-
Male
-
Microbial Sensitivity Tests
-
Mycobacterium tuberculosis / drug effects
-
Mycobacterium tuberculosis / isolation & purification
-
Tuberculosis, Multidrug-Resistant / drug therapy
-
Tuberculosis, Multidrug-Resistant / microbiology
-
Tuberculosis, Pleural / drug therapy*
-
Tuberculosis, Pleural / microbiology
Substances
-
Antitubercular Agents
-
Fluoroquinolones