Abstract
NADH- or NADPH-oxidase activity was cytochemically detected at the ultrastructural level during the process of interaction between Trypanosoma cruzi and activated mouse peritoneal macrophages. The reaction product, indicative of enzyme activity, was found in the portion of the plasma membrane of the macrophages to which the parasites attached. It was also found in the membrane which surrounds endocytic vacuoles containing ingested parasites.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Host-Parasite Interactions
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Macrophage Activation*
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Macrophages / enzymology
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Macrophages / parasitology*
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Macrophages / ultrastructure
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Mice
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Microscopy, Electron
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Multienzyme Complexes / analysis*
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NADH, NADPH Oxidoreductases / analysis*
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NADPH Oxidases
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Trypanosoma cruzi / physiology*
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Trypanosoma cruzi / ultrastructure
Substances
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Multienzyme Complexes
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NADH oxidase
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NADH, NADPH Oxidoreductases
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NADPH Oxidases