Acute Pancreatitis as the Initial Manifestation in 2 Cases of COVID-19 in Wuhan, China

Kaige Wang; Jianfei Luo; Fen Tan; Jiasheng Liu; Zhong Ni; Dan Liu; Panwen Tian; Weimin Li

doi:10.1093/ofid/ofaa324

Acute Pancreatitis as the Initial Manifestation in 2 Cases of COVID-19 in Wuhan, China

Open Forum Infect Dis. 2020 Aug 7;7(9):ofaa324. doi: 10.1093/ofid/ofaa324. eCollection 2020 Sep.

Authors

Kaige Wang¹, Jianfei Luo², Fen Tan³, Jiasheng Liu², Zhong Ni¹, Dan Liu¹, Panwen Tian⁴, Weimin Li¹

Affiliations

¹ Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, P.R. China.
² Department of Gastrointestinal Surgery, Renmin Hospitai of Wuhan Uiniversity, Wuhan, P.R. China.
³ Department of Pulmonary and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Respiratory Disease Research Institute of Hunan Province, Changsha, P.R. China.
⁴ Department of Pulmonary and Critical Care Medicine, Lung Cancer Treatment Center, West China Hospital, Sichuan University, Chengdu, P.R. China.

Abstract

Clinical data on coronavirus disease 2019 (COVID-19) with pancreatic injury are extremely limited. An acute manifestation of acute pancreatitis in COVID-19 has not been reported. We describe here 2 cases of COVID-19 with acute pancreatitis as the initial manifestation in Wuhan, China. Patient 1 died despite maximal mechanical ventilatory support and circulation support, while patient 2 was finally discharged after showing significant improvement. Low T cells in peripheral blood may indicate a poor outcome.

Keywords: COVID-19; Wuhan; acute pancreatitis; initial manifestation.