Microscopic brain tumor detection and classification using 3D CNN and feature selection architecture

Microsc Res Tech. 2021 Jan;84(1):133-149. doi: 10.1002/jemt.23597. Epub 2020 Sep 21.

Abstract

Brain tumor is one of the most dreadful natures of cancer and caused a huge number of deaths among kids and adults from the past few years. According to WHO standard, the 700,000 humans are being with a brain tumor and around 86,000 are diagnosed since 2019. While the total number of deaths due to brain tumors is 16,830 since 2019 and the average survival rate is 35%. Therefore, automated techniques are needed to grade brain tumors precisely from MRI scans. In this work, a new deep learning-based method is proposed for microscopic brain tumor detection and tumor type classification. A 3D convolutional neural network (CNN) architecture is designed at the first step to extract brain tumor and extracted tumors are passed to a pretrained CNN model for feature extraction. The extracted features are transferred to the correlation-based selection method and as the output, the best features are selected. These selected features are validated through feed-forward neural network for final classification. Three BraTS datasets 2015, 2017, and 2018 are utilized for experiments, validation, and accomplished an accuracy of 98.32, 96.97, and 92.67%, respectively. A comparison with existing techniques shows the proposed design yields comparable accuracy.

Keywords: 3D CNN; World Health Organization (WHO); cancer; healthcare; public health.

MeSH terms

  • Adult
  • Brain / diagnostic imaging
  • Brain Neoplasms* / diagnostic imaging
  • Humans
  • Magnetic Resonance Imaging
  • Neural Networks, Computer*