Genome-wide association study identifies 48 common genetic variants associated with handedness

Affiliations

• ¹ The University of Queensland Diamantina Institute, The University of Queensland, Woolloongabba, Queensland, Australia.
• ² 23andMe, Inc., Sunnyvale, CA, USA.
• ³ Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
• ⁴ Department of Psychology, Virginia Commonwealth University, Richmond, VA, USA.
• ⁵ Karabuk University, Faculty of Business, Karabük, Turkey.
• ⁶ NORMENT, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
• ⁷ Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
• ⁸ Human Genetics, Wellcome Sanger Institute, Hinxton, UK.
• ⁹ MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
• ¹⁰ Wellcome-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
• ¹¹ Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland.
• ¹² Department of Psychiatry, UMC Utrecht Brain Center, University Utrecht, Utrecht, The Netherlands.
• ¹³ Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands.
• ¹⁴ Amsterdam Public Health research institute, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
• ¹⁵ Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
• ¹⁶ Population Health Sciences, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
• ¹⁷ Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.
• ¹⁸ Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.
• ¹⁹ Harvard Medical School, Boston, MA, USA.
• ²⁰ Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
• ²¹ Department of Psychology, University of Edinburgh, Edinburgh, UK.
• ²² Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.
• ²³ William Harvey Research Institute, Barts and the London Medical School, and the Centre for Genomic Health, Queen Mary University of London, London, UK.
• ²⁴ Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA, USA.
• ²⁵ Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
• ²⁶ Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
• ²⁷ Folkhälsan Research Center, Helsinki, Finland.
• ²⁸ Singapore Institute for Clinical Sciences, Agency for Science Technology and Research, Singapore, Singapore.
• ²⁹ Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
• ³⁰ Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
• ³¹ Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
• ³² Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
• ³³ German Center for Diabetes Research (DZD), München-Neuherberg, Neuherberg, Germany.
• ³⁴ University Clinic and Outpatient Clinic for Psychiatry, Psychotherapy and Psychosomatics, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.
• ³⁵ Department of Epidemiology, Richard M. Fairbanks School of Public Health, Indiana University, Indianapolis, IN, USA.
• ³⁶ Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis, IN, USA.
• ³⁷ Institute of Biological Psychiatry, Mental Health Services of Copenhagen, Copenhagen, Denmark.
• ³⁸ Danish Headache Center, Copenhagen University Hospital, Glostrup, Denmark.
• ³⁹ MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
• ⁴⁰ Institute for Molecular Medicine FIMM, University of Helsinki, Helsinki, Finland.
• ⁴¹ Institute for Biomedicine, Eurac Research, Bolzano, Italy.
• ⁴² Division of Endocrinology, Boston Children's Hospital, Boston, MA, USA.
• ⁴³ Department of Genetics, Harvard Medical School, Boston, MA, USA.
• ⁴⁴ Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.
• ⁴⁵ Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
• ⁴⁶ Department of Public Health, University of Helsinki, Helsinki, Finland.
• ⁴⁷ Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
• ⁴⁸ Public Health and Primary Care, University of Cambridge, Cambridge, UK.
• ⁴⁹ Hannover Unified Biobank, Hannover Medical School, Hannover, Germany.
• ⁵⁰ Center for Primary Care and Public Health, University of Lausanne, Lausanne, Switzerland.
• ⁵¹ Swiss Institute of Bioinformatics, Lausanne, Switzerland.
• ⁵² Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland.
• ⁵³ Turku Institute for Advanced Studies, University of Turku, Turku, Finland.
• ⁵⁴ Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
• ⁵⁵ The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
• ⁵⁶ The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
• ⁵⁷ deCODE Genetics, Reykjavik, Iceland.
• ⁵⁸ Department of Medicine, Internal Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
• ⁵⁹ Bristol Medical School, University of Bristol, Bristol, UK.
• ⁶⁰ Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
• ⁶¹ Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.
• ⁶² Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK.
• ⁶³ Human Genetics, Genentech, South San Francisco, CA, USA.
• ⁶⁴ Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
• ⁶⁵ Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
• ⁶⁶ Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
• ⁶⁷ Service of Clinical Chemistry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
• ⁶⁸ School of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia.
• ⁶⁹ Department of Human Genetics, University California Los Angeles, Los Angeles, CA, USA.
• ⁷⁰ Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University California Los Angeles, Los Angeles, CA, USA.
• ⁷¹ Department of Psychiatry, Erasmus University Medical Center, Rotterdam, The Netherlands.
• ⁷² Department of Computer Science, Columbia University, New York, NY, USA.
• ⁷³ Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
• ⁷⁴ MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
• ⁷⁵ Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.
• ⁷⁶ Department of Psychiatry, Amsterdam UMC, VU University, Amsterdam, The Netherlands.
• ⁷⁷ Department of Public Health, University of Split School of Medicine, Split, Croatia.
• ⁷⁸ Research Unit, Psychiatric Hospital Sveti Ivan, Zagreb, Croatia.
• ⁷⁹ Section of Statistical Multi-Omics, Department of Clinical and Experimental Medicine, University of Surrey, Guildford, UK.
• ⁸⁰ Section of Genomics of Common Disease, Department of Medicine, Imperial College London, London, UK.
• ⁸¹ Centre for Global Health Research, The Usher Institute, University of Edinburgh, Edinburgh, UK.
• ⁸² Department of Psychiatry and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
• ⁸³ Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA.
• ⁸⁴ Max Planck Institute for Psycholinguistics, Wundtlaan, Nijmegen, The Netherlands.
• ⁸⁵ Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands.
• ⁸⁶ Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK.
• ⁸⁷ Centre for Cognitive Ageing and Cognitive Epidemilogy, University of Edinburgh, Edinburgh, UK.
• ⁸⁸ Behavioural Science Institute, Radboud University, Nijmegen, The Netherlands.
• ⁸⁹ Human Genetics, GlaxoSmithKline, Collegeville, PA, USA.
• ⁹⁰ The Lundbeck Foundation's IPSYCH Initiative, Copenhagen, Denmark.
• ⁹¹ Institute of Epidemiology, Helmholtz Center, Munich, Germany.
• ⁹² Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia.
• ⁹³ Centre for Advanced Imaging, The University of Queensland, Brisbane, Queensland, Australia.
• ⁹⁴ Department of Epidemiology, Harvard T. H. Chan School of Public Health, Harvard Medical School, Boston, MA, USA.
• ⁹⁵ Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
• ⁹⁶ Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.
• ⁹⁷ Analytic and Translational Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
• ⁹⁸ The University of Queensland Diamantina Institute, The University of Queensland, Woolloongabba, Queensland, Australia. [email protected].
• ⁹⁹ MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK. [email protected].
• ¹⁰⁰ The University of Queensland Diamantina Institute, The University of Queensland, Woolloongabba, Queensland, Australia. [email protected].
• ¹⁰¹ Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia. [email protected].