Feasibility of magnetic resonance guided radiotherapy for the treatment of bladder cancer

A Hunt; I Hanson; A Dunlop; H Barnes; L Bower; J Chick; C Cruickshank; E Hall; T Herbert; R Lawes; D McQuaid; H McNair; A Mitchell; J Mohajer; T Morgan; U Oelfke; G Smith; S Nill; R Huddart; S Hafeez

doi:10.1016/j.ctro.2020.09.002

Feasibility of magnetic resonance guided radiotherapy for the treatment of bladder cancer

Clin Transl Radiat Oncol. 2020 Sep 11:25:46-51. doi: 10.1016/j.ctro.2020.09.002. eCollection 2020 Nov.

Authors

A Hunt^{1

2}, I Hanson³, A Dunlop³, H Barnes², L Bower^{1

2}, J Chick³, C Cruickshank⁴, E Hall⁴, T Herbert², R Lawes², D McQuaid³, H McNair^{1

2}, A Mitchell³, J Mohajer³, T Morgan^{1

2}, U Oelfke³, G Smith², S Nill³, R Huddart^{1

2}, S Hafeez^{1

2}

Affiliations

¹ The Institute of Cancer Research, London, UK.
² The Royal Marsden NHS Foundation Trust, London, UK.
³ The Joint Department of Physics at The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London, UK.
⁴ Clinical Trials and Statistics Unit, The Institute of Cancer Research, London, UK.

Abstract

Whole bladder magnetic resonance image-guided radiotherapy using the 1.5 Telsa MR-linac is feasible. Full online adaptive planning workflow based on the anatomy seen at each fraction was performed. This was delivered within 45 min. Intra-fraction bladder filling did not compromise target coverage. Patients reported acceptable tolerance of treatment.

Keywords: Adaptive radiotherapy; MR-guided radiotherapy; MR-linac; bladder cancer.

Abstract

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