Persistent Agminated CD30+ Lymphoproliferative Disorder

J Drugs Dermatol. 2020 Oct 1;19(10):1005-1007.

Abstract

Lymphomatoid papulosis (LyP) is a chronic skin condition, characterized by recurrent eruptions of papules and nodules with or without central necrosis that spontaneously resolve. This condition was originally described by Macaulay in 1968 as a self-healing rhythmical paradoxical eruption that was clinically benign yet histologically malignant.1 Clinically, it is defined by papules that wax and wane, are generally less than 1cm in diameter, and heal spontaneously after 6–8 weeks with subsequent scarring.2

Publication types

  • Case Reports

MeSH terms

  • Administration, Cutaneous
  • Adult
  • Clobetasol / administration & dosage
  • Clobetasol / therapeutic use
  • Diagnosis, Differential
  • Female
  • Humans
  • Leg
  • Lymphomatoid Papulosis / diagnosis*
  • Lymphomatoid Papulosis / drug therapy
  • Lymphomatoid Papulosis / pathology
  • Skin Neoplasms / diagnosis*
  • Skin Neoplasms / drug therapy
  • Skin Neoplasms / pathology
  • T-Lymphocyte Subsets*

Substances

  • Clobetasol